Fort Myers is served K-12 education by the Lee County School District, the 9th largest district in Florida and among the 50 largest school systems in the United States. Fort Myers High School is regularly identified as a national top 100 best high schools and Dunbar High School a STEM magnet school of merit and the first Microsoft Certified High School.

Higher education needs are met by Florida Gulf Coast University and Edison State College. Seven private college campuses and 33 private K-12 schools augment the public education system in Lee County.